Drug Resistance is a universal defense mechanism of a living system toward a component that threats its survival or impedes its development. It occurs when pathogens (bacteria, viruses, fungi, parasites) or cancerous cells evolve to withstand the effects of medications that once effectively treated them. This phenomenon is a significant challenge in the treatment of numerous infectious diseases and cancer. The group Drug Advances & Innovations seeks to develop new drugs and alternative treatment solutions to circumvent drug resistance phenomena. Our research activities focus on the design of new families of bioactive molecules, the identification and targeting of new mechanisms of action, and the progress of drugs through early preclinical development processes.
Research group expertises:
- Organic synthesis
- Medicinal Chemistry
- Drug Design
- Dockings
- Hit-to-lead Optimization
- Drug Formulation
- Pharmacology
- Bioanalytics
- Pre-CMC Development